Publications
Inducible Gene Expression
a. Lin, W., Albanese, C., Pestell, R.G., Lawrence, D.S., Spatially discrete, light-driven protein expression. Chem Biol. 2002 Dec; 9(12):1347-53.
b. Albanese C, Reutens AT, Bouzahzah B, Fu M, D'Amico M, Link T, Nicholson R, Depinho RA, Pestell RG., Sustained mammary gland-directed, ponasterone A-inducible expression in transgenic mice. FASEB J. 2000 May;14(7):877-84.
c. Albanese C, Hulit J, Sakamaki T, Pestell RG., Recent advances in inducible expression in transgenic mice. Semin Cell Dev Biol. 2002 Apr;13(2):129-41. Review
d. Sakamaki T, Casimiro MC, Ju X, Quong AA, Katiyar S, Liu M, Jiao X, Li A, Zhang X, Lu Y, Wang C, Byers S, Nicholson R, Link T, Shemluck M, Yang J, Fricke ST, Novikoff PM, Papanikolaou A, Arnold A, Albanese C, Pestell R. Cyclin D1 determines mitochondrial function in vivo. Mol Cell Biol. 2006 Jul;26(14):5449-69.
e. Wang C, Pattabiraman N, Zhou JN, Fu M, Sakamaki T, Albanese C, Li Z, Wu K, Hulit J, Neumeister P, Novikoff PM, Brownlee M, Scherer PE, Jones JG, Whitney KD, Donehower LA, Harris EL, Rohan T, Johns DC, Pestell RG., Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation.
Mol Cell Biol. 2003 Sep;23(17):6159-73.
f. Pestell RG. Light-Activated Gene Therapy, New Selective Therapies for Disease. The Journal of Nuclear Medicine 2006 Dec;47(12).
Preventing Cardiac damage from chemotherapy (used for cancer).
Pestell RG, Barr AL, Brand G. Vitamin C and congestive cardiac failure. Med J Aust. 1987 Aug 3;147(3):153-4. No abstract available. PMID: 3600482 (described the use of Desferroxamine to reduce cardiac toxicity in patient).
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Ashton AW, Watanabe G, Albanese C, Harrington EO, Ware JA, Pestell RG. Protein kinase Cdelta inhibition of S-phase transition in capillary endothelial cells involves the cyclin-dependent kinase inhibitor p27(Kip1).J Biol Chem. 1999 Jul 23;274(30):20805-11.PMID:10409620
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Petkova SB, Ashton A, Bouzahzah B, Huang H, Pestell RG, Tanowitz HB. Cell cycle molecules and diseases of the cardiovascular system. Front Biosci. 2000 Apr 1;5:D452-60. Review.PMID:10762598.
Nam YJ, Mani K, Ashton AW, Peng CF, Krishnamurthy B, Hayakawa Y, Lee P, Korsmeyer SJ, Kitsis RN. Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions. Mol Cell. 2004 Sep 24;15(6):901-12.PMID:15383280.
Mercier I, Vuolo M, Madan R, Xue X, Levalley AJ, Ashton AW, Jasmin JF, Czaja MT, Lin EY, Armstrong RC, Pollard JW, Kitsis RN. ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance. Cell Death Differ. 2005 Jun;12(6):682-6. PMID:15861191
Nam YJ, Mani K, Wu L, Peng CF, Calvert JW, Foo RS, Krishnamurthy B, Miao W, Ashton AW, Lefer DJ, Kitsis RN. The apoptosis inhibitor ARC undergoes ubiquitin-proteasomal-mediated degradation in response to death stimuli: identification of a degradation-resistant mutant. J Biol Chem. 2007 Feb 23;282(8):5522-8. Epub 2006 Dec 1.PMID:17142452.
Foo RS, Nam YJ, Ostreicher MJ, Metzl MD, Whelan RS, Peng CF, Ashton AW, Fu W, Mani K, Chin SF, Provenzano E, Ellis I, Figg N, Pinder S, Bennett MR, Caldas C, Kitsis RN. Regulation of p53 tetramerization and nuclear export by ARC.Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20826-31. Epub 2007 Dec 17.PMID:18087040
Gavrilov S, Nührenberg TG, Ashton AW, Peng CF, Moore JC, Konstantinidis K, Mummery CL, Kitsis RN. Tbx6 is a determinant of cardiac and neural cell fate decisions in multipotent P19CL6 cells. Differentiation. 2012 Sep;84(2):176-84. doi: 10.1016/j.diff.2012.04.007. Epub 2012 Jun 19.PMID:22721678.